A group of cells is tested for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. Based on this information, how many pictograms of DNA would you expect to find at the end of the S phase and the end of the G2 phase?

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Answer:

At the end of S phase: 16

At the end of G2 phase: 16

Explanation:

The cells formed by the end of mitosis had 8 picograms of DNA. These cells entered in the process of the cell cycle. The G1 phase of interphase would duplicate their cellular content. S phase of interphase would include DNA replication. During this phase, the content of DNA in the nuclei of these cells would be doubled. By the end of the S phase, there would be 16 picograms of DNA in nuclei of each of these cells.

These cells would enter the G2 phase where the DNA content is maintained. Therefore, by the end of the G2 phase, each of these cells would have 16 picograms of DNA.

We expect 16 pictograms of DNA at the end of the S phase and the end of the G2 phase.

16 pictograms of DNA we expect at the end of the S phase and the end of the G2 phase because DNA replication occurs during S phase in which extra copy of DNA is produced. S phase is also called synthesis phase in which DNA replication occurs.

While on the other hand, G2 phase is a period of rapid cell growth and protein synthesis during which the cell prepares itself for mitosis. This phase also occurs after S phase so we can conclude that 16 pictograms of DNA we expect at the end of the S phase and the end of the G2 phase which are equally distributed among daughter cells at the end of mitosis.

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