The correct answer is multinucleate tissues, occurring naturally during the physical body work in conjugation with the plasma of the membranes of the cells. In summary, the skeletal cells are multinucleate because they are the result of the union between the muscular cells and the soft cells of the muscle. The reason they are multinucleate is because they facilitate the circulation of stem cells during the most demanding muscular movements. Stem cells help multinucleate tissue communicate faster.