How can a problem in one body system cause a cascade effect on multiple body systems? use anna as an example to illustrate your response.

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This is a matter of cascading failure in which interrelated body parts are affected by dysfunctionality of each other. There is a zipper-like effect and the defect in one structural component leads to the production of compounds which affect other parts also, for example, ischemic cascade in which toxic are released which damage other body parts as well. 
In Anna's case, the splenic artery was affected by the sickle cells, which led to the accumulation of blood inside spleen and led to spleen sequestration. This further degraded her already present anemic condition, and the body was not able to receive ample nutrients from the blood supply and thus, kidneys were damaged severely, as the blood could not be filtered and high levels of toxins accumulated inside her body, which caused damage to other parts and her death also.

A cascade effect is illustrated by a series of events that are directly or indirectly linked to one another. This is the reason why one body system causes a cascade effect on multiple body systems.

What do you mean by the Cascade effect?

The cascade effect may be defined as a series of events that occurs when an event in a system has a negative impact on other, related systems.

An example of cascade effects includes the rate of high blood pressure which changes the whole functioning of the body in humans. The sudden rise in blood pressure affects the heart rate, excessive sweating, it changes the functions of the nervous system, etc.

Therefore, it may lead to one body system causing a cascade effect on multiple body systems.

To learn more about Cascade effects, refer to the link:

https://brainly.com/question/16403538