Candy says Curley's "pants is full of ants" to mean that he cannot sit still, and Curley and his new bride do not get along very well, as explained below.
What does "pants full of ants" mean?
The expression "pants full of ants" is used to refer to someone who cannot sit still, who is always up and about doing something. In the novel "Of Mice and Men," Candy uses this expression to talk about Curley.
Curley cannot sit still in the sense that he is always concerned about what his bride is doing. He and his wife do not get along very well. Curley is quite controlling and jealous, whereas his wife always seems to be making eyes at someone. That leads to problems in their relationship, which they do not seem to try to fix.
With the explanation above in mind, we can conclude that the answer provided is correct.
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