Prostaglandins, commonly referred to as tissue hormones, function locally to help control bodily functions like breathing, blood pressure, and digestive secretions.
Your risk of developing unusually thick uterine lining increases as you eat more meals high in estrogen. Because of this, as it starts to degrade throughout the menstrual cycle, this process generates more prostaglandins, increasing pain.
Prostaglandins operate directly on nerve endings to induce pain when they are present in high amounts. But more often than not, they sharply increase pain sensitivity at low dosages. Even ordinarily harmless stimuli could become painful due to changed pain thresholds.
The production of the inflammatory response is significantly influenced by prostaglandins. They contribute to the primary symptoms of acute inflammation and their production is markedly elevated in tissue that is inflamed.
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