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Based on a microbe's protein composition, a method called MALDI-TOF may assess a culture or a patient sample in a matter of minutes.
What is the purpose of a MALDI-TOF?
In the clinical microbiology laboratory, matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry (MS) has gained popularity as a method for the quick and precise identification of bacteria, mycobacteria, and some fungal infections.
What is the MALDI-guiding TOF's principle?
Principle and methodology of MALDI. The sample is prepared for MALDI MS analysis by combining or coating it with a solution of matrix, an organic substance that absorbs energy. The sample trapped inside the matrix crystallizes along with the matrix when it dries and crystallizes.
What is the purpose of MALDI-TOF in microbiology?
A strong analytical mass spectrometry method known as matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) has produced a number of diagnostic and clinical applications, particularly for the identification of microorganisms for medical diagnosis.
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