A client is prescribed amitriptyline, an antidepressant for incontinence. the nurse understands that this drug is an effective treatment for which reason?

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A client is prescribed amitriptyline, an antidepressant for incontinence. the nurse understands that this drug is an effective treatment for following reasons:

  • Increases bladder neck resistance
  • Decreases involuntary bladder contractions

What is amitriptyline?

Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat cyclic vomiting syndrome (CVS), major depressive disorder and a variety of pain syndromes from neuropathic pain to fibromyalgia to migraine and tension headaches. Due to the frequency and prominence of side effects, amitriptyline is generally considered a second-line therapy for these indications.

The most common side effects are dry mouth, drowsiness, dizziness, constipation, and weight gain. Of note is sexual dysfunction, observed primarily in males. Glaucoma, liver toxicity and abnormal heart rhythms are rare but serious side effects. Blood levels of amitriptyline vary significantly from one person to another, and amitriptyline interacts with many other medications potentially aggravating its side effects.

To learn more about Amitriptyline

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