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Helper t-cells identify antigens and then multiply and trigger the production of other kinds of immune cells.

What are helper T-cells?

Helper T-cells are one of the main types of immune cells. They detect infections and activate other immune cells to fight the infection.

Your thymus develops helper T-cells. The thymus is a small gland in the front of your chest. The other types of T-cells include:

  • Cytotoxic T-cells, which fight infections.
  • Regulatory T-cells, which regulate or suppress other immune cells when needed.
  • NKT-cells, which can enhance immunity in general.

What are the subtypes of helper T-cells?

When helper T-cells detect an infection, they form into one of two subtypes:

  1. TH1 helper cells release a molecule that activates a type of cell called a macrophage. Macrophages are specialized cells that help eliminate foreign substances from your body. TH1 cells also activate cytotoxic T-cells.
  2. TH2 helper cells release molecules that activate B-cells. B-cells create antibodies. They also release cells that cause coughing, sneezing or diarrhea to help your body get rid of foreign substances. This group of T-cells helps generate allergy antibodies.

Learn more about helper T-cells

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