People overusing certain antacids are prone to indigestion because it causes a rise in pH thereby leading to less pepsinogen being activated.
This is referred to a substance which neutralizes the acidity of the stomach thereby relieving heartburns etc.
They create an alkaline environment and enzymes such as pepsinogen are stable in acidic environment which denatures it and makes it impossible for its activation thereby leading to the people having  difficulties digesting certain foods such as protein.
Read more about Antacid here https://brainly.com/question/5328009
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