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Which of the following best describes the significance of the TATA box in eukaryotic promoters?

A) It is the recognition site for a specific transcription factor.
B) It sets the reading frame of the mRNA.
C) It prevents supercoiling of the DNA near the start site.
D) It is the recognition site for ribosomal binding.
E) Its significance has not yet been determined.

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Answer:

The correct option is A.

Explanation:

TATA box refers to a  non coding sequence of DNA that is found in the promoter regions of eukaryotic genes. The TATA box serves as the binding sites for certain proteins and some transcriptions factors in eukaryotic genes; it signifies the points where transcription begins. Transcription is the process by which the genetic information in DNA is replicated into an mRNA. This is the first step in protein synthesis.  The name TATA was derived from the nucleotide bases that are always present in large number a the site. T stands for thymine while A represents the adenine base.  

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