a 67-year-old man is admitted to the hospital with pneumonia. he reports to the nurse that he has chronic arthritis and circulation problems. further assessment by the nurse reveals that the patient has a history of mild hypertension. he explains that he owns a business and lives alone. the nurse determines that he is within the normal weight range for his height and age but has a fondness for spicy foods and sweets. which of the mentioned patient variables will have the greatest impact on the effectiveness of the patient's drug therapy?